Monday, July 14, 2008

Bio-Tag:Triclosan


©2007 COX Washington News Bureau. Story about how using antibacterial soap and hand sanitizers are actually bad for you and can lead to you being more prone to get sick.

Click here to watch video.

Wikipedia states:

Resistance concerns: An article coauthored by Dr. Stuart Levy in the August 6, 1998 issue of Nature[12] warned that triclosan's overuse could cause resistant strains of bacteria to develop, in much the same way that antibiotic-resistant bacterial strains are emerging, based on speculation that triclosan behaved like an antibiotic. Based on this speculation, in 2003, the Sunday Herald newspaper reported that some UK supermarkets and other retailers were considering phasing out products containing triclosan.

It has since been shown that the laboratory method used by Dr. Levy was not effective in predicting bacterial resistance for biocides like triclosan, based on work by Dr. Peter Gilbert in the UK, whose research is supported by Procter & Gamble [1].[13] At least seven peer-reviewed and published studies have been conducted demonstrating that triclosan is not significantly associated with bacterial resistance over the short term, including one study coauthored by Dr. Levy, published in August of 2004 in Antimicrobial Agents and Chemotherapy.[14]
Some level of triclosan resistance can occur in some microorganisms, but the larger concern is with the potential for cross-resistance or co-resistance to other antimicrobials. Studies investigating this possibility have been limited.[15]

Health concerns:Reports have suggested that triclosan can combine with chlorine in tap water to form chloroform gas,[16] which the United States Environmental Protection Agency classifies as a probable human carcinogen. As a result, triclosan was the target of a UK cancer alert, even though the study showed that the amount of chloroform generated was less than amounts often present in chlorinated drinking waters.

Triclosan reacts with the free chlorine in tap water to also produce lesser amounts of other compounds, like 2,4-dichlorophenol.[16] Most of these intermediates convert into dioxins upon exposure to UV radiation (from the sun or other sources). Although small amounts of dioxins are produced, there is a great deal of concern over this effect because dioxins are extremely toxic and are very potent endocrine disruptors. They are also chemically very stable, so that they are eliminated from the body very slowly (they can bioaccumulate to dangerous levels), and they persist in the environment for a very long time.
Triclosan is chemically somewhat similar to the dioxin class of compounds. Its production leads to small amounts of residual polychlorinated dioxins, and polychlorinated furans which are contained in small amounts, in the products that are using it.
A 2006 study concluded that low doses of triclosan act as an endocrine disruptor in the North American bullfrog.[17] The hypothesis proposed is that triclosan blocks the metabolism of thyroid hormone, because it chemically mimics thyroid hormone, and binds to the hormone receptor sites, blocking them, so that normal hormones cannot be utilized. Triclosan has also been found in both the bile of fish living downstream from waste water processing plants and in human breast milk.[18] The negative effects of Triclosan on the environment and its questionable benefits in toothpastes[19] has led to the Swedish Naturskyddsföreningen to recommend not using triclosan in toothpaste.[20]

Triclosan is used in many common household products including Clearasil Daily Face Wash, Dentyl mouthwash, Dawn, the Colgate Total range, Crest Cavity Protection, Softsoap, Dial, Right Guard deodorant, Sensodyne Total Care, Old Spice and Mentadent.

At this time, in the United States, manufacturers of products containing triclosan must say so somewhere on the label.
The ADA (American Dental Association) published a response to the concerns stemming from the Virginia Tech study stating that Triclosan in toothpaste is not relevant.

In one study, recently accepted for publication in the journal Environmental Health Perspectives and made available online, Isaac Pessah, PhD, director of the U.C. Davis Children's Center for Environmental Health, looked at how triclosan may affect the brain. Pessah's test-tube study found that the chemical attached itself to special "receptor" molecules on the surface of cells. This raises calcium levels inside the cell. Cells overloaded with calcium get overexcited. In the brain, these overexcited cells may burn out neural circuits, which could lead to an imbalance that affects mental development. Some people may carry a mutated gene that makes it easier for triclosan to attach to their cells. That could make them more vulnerable to any effects triclosan may cause.[21]

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Bio-Tag raises awareness of dangerous toxins present in the physical environment through the deployment of searchable word “markers” made from natural materials. Hopefully, these typographic deployments will solicit a curiosity that will draw people into personal research and action. The motivation for these actions is to address the lack of public knowledge and the hopeful elimination of toxins that are present in food, the body, the home, and the environment. The scope of the project includes these toxin categories: Agricultural Toxins, Air Pollutants, Biological Contaminants, Carcinogens, Chemicals, Extremely Hazardous Substances, Microorganisms, Multimedia Pollutants, Ozone, Radiation, Soil Contaminants, Toxic Substances, and Water Pollutants. This is an ongoing project www.finishing-school.net/biotag.html

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